It is celebrated on April 25 of each year.
Agios Makedonios II, as elder and custodian of Hagia Sophia, for his piety, in which he was educated by his uncle Patriarch Gennadios, was called to administer the Ecumenical throne (496-511), instead of Patriarch Eufimios, who was exiled to Euchaita.
The people had great love for his person. However, the heretical emperor Anastasios Dikoros (491-518), asked Macedonia for a letter – which Anastasios had given to Macedonian’s predecessor, Euphymius, and then he had given to Macedonian – with which he assured in his own writing, that he would observe inviolable the doctrines of the Church. An assurance he brutally violated.
Macedonius refused to give it to him, and Anastasius, enraged, deposed him, and exiled him first to Chalcedon and then to Euchaita. But due to the incursions of the Huns in Pontus, he fled to Gangra, where he died in 517 AD. He turned out to be a true bishop, a defender of Orthodoxy and the Church against imperial arbitrariness.
